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박미정 ( Park Mi-Jung ) - 대불대학교 간호학과
최명애 ( Choe Myoung-Ae ) - 서울대학교 간호대학
김금순 ( Kim Keum-Soon ) - 서울대학교 간호대학
홍해숙 ( Hong Hae-Sook ) - 경북대학교 간호대학
이경숙 ( Lee Kyong-Sook ) - 원주대학 간호과
정재심 ( Jeong Jae-Sim ) - 울산대학교 의과대학 임상전문간호학
채영란 ( Chae Young-Ran ) - 강원대학교 의과대학 간호학과
안경주 ( An Gyeong-Ju ) - 대구가톨릭대학교 의과대학 간호학과
신기수 ( Shin Gi-Soo ) - 적십자간호대학
최정안 ( Choi Jung-An ) - 서울대학교 간호과학연구소
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Abstract
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Purpose: Irritable bowel syndrome (IBS) is frequently yet little understood disease. Review was performed to promote understanding on the characteristics, pathophysiology, and risk factors of IBS.
Content: IBS is characterized by abdominal discomfort associated with pain and altered bowel function; structural and biochemical abnormalities are absent. Generally IBS is more prevalent in women and people with higher educational and social background, but there are some controversies. IBS is diagnosed by the Rome II or Manning criteria after excluding organic gastrointestinal diseases. The pathophysioloy is explained by abnormal control mechanism of central and enteric nervous system. Mucosal immunity, secretions, and neurotransmitter are also associated with the hypersensitivity and motility change of bowel function. Stress is known as a major triggering factor and contributed to symptoms. Other risk factors are genetic elements, childhood experiences, inflammation, anxiety, depression, diet, and sleep disorders.
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KeyWords
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과민성 장 증후군, 역학적 특성, 병태생리, 위험요인
Irritable bowel syndrome, Epidemiolgy, Pathophysiology, Risk factors
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원문 및 링크아웃 정보
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등재저널 정보
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